BGV HEALTH NEWS Here
you will find updates on any health concerns that are being investigated
by the BGV Club and any that may come to light where the committee has
decided that the numbers drawn to their attention warrant further
the Breed Health Survey undertaken in 2016 shows that, apart from the
known penetration of POAG in PBGVs and a concern over cases of Epilepsy, there
is currently no development of other major health problems in our breeds.
ON ‘HEREDITARY CLEAR’ STATUS POSTPONED TO 2023
the announcement that The Kennel Club will limit the assignment of ‘hereditary
clear’ status of registered dogs to two generations, the organisation has
announced that this change is now set to be implemented as of January 2023.
decision to restrict hereditary status was made by The Kennel Club Board in
2018 on the recommendation of the Dog Health Group and followed a Kennel Club
study published in the journal of Canine Genetics and Epidemiology. This change
was put forward to safeguard against the impact that dogs with an incorrect
‘hereditary clear’ status could have on health issues within a breed.
clear status is given to dogs that are determined to be free of specific
genetic material linked to a particular inherited disease. The Kennel Club’s
registration system assigns a dog this status if their parents are known to be
clear, either because they have both been DNA tested as clear, or because they
are hereditary clear themselves.
could be mistakenly given a false hereditary clear status for a number of
reasons; for example, if there has been a failure of laboratory protocols,
pedigree errors, or incorrectly recorded parentage. In these instances, it is unlikely that the
inaccuracies would be noticed immediately, but rather that several generations
later many dogs throughout the breed descended from the individual with the
original incorrect status will also have erroneous hereditary status, and the
well-intended mating of two such apparently hereditary clear dogs risks
producing affected puppies.
Kennel Club research analysed the risks faced by a population following the
incorrect assignment of hereditary status and determined that the rate of dogs
with false hereditary clear status could rise considerably over a fairly small
number of generations, particularly for genetic conditions that are more
reduce the knock-on effect of these errors, and the risk of unintentionally
breeding affected puppies, The Kennel Club will be ensuring that from January
2023, the ‘hereditary clear status’ will be limited to two generations, unless
lineage is verified by DNA parentage profiling recorded by The Kennel Club. DNA parentage profiling is a separate
procedure to screening DNA for disease causing mutations but can often be
carried out at the same time by the same laboratory.
scheduled to come into effect in January 2022, this has now been postponed to
2023 to allow for necessary development work to be completed and in order for
‘hereditary clear’ status to be as effective and reliable as possible.
Club Press Office
over a year, PBGV owners helped the Animal Health Trust by allowing their PBGVs
height to be measured. This was to pursue the theory that there might be
a link between the Primary Open Angle Glaucoma (POAG) mutation and height in
the PBGV. The POAG mutation is in a gene called ADAMTS17. Humans
that have mutations in this gene are invariably of short stature, as the gene
also affects bone development.
information collected enabled the AHT to pull data together showing whether
PBGV height is correlated with genotype. In other words, were the affected and/or
carriers slightly shorter than the clear/normal dogs?
to submission to a scientific journal for publication, an early abstract of the
findings was presented at the May 2018 European College of Veterinary
Ophthalmologists (ECVO) Conference in Florence. Further details on this
were in the Winter 2018 Voice.
RECOGNITION IN EPILEPTIC DOGS
Royal Veterinary College is conducting a study into long term changes in dogs
that happen before a seizure in the hope that they may be able to predict
seizure activity. In this way owners will know when to give their dogs
anti-epileptic drugs to intervene and thus prevent the seizure from
your BGV has regular seizures and you would like to be involved in this study,
the link here takes you to the RVC website where you can complete their
fill out this questionnaire to let them know about your dog and
they will be in touch: https://www.surveymonkey.co.uk/r/PREDICTstudy
Remember - If you are worried about
your BGV's health and suspect it may be related to one of the known health
issues in the breed, the BGV Club Health Sub-Committee is here
to support you.
If you have any concerns about your BGV's well-being which appear to be related to any of the known health problems in the breed, let us know. We are here to support you.